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What is Oxytocin Peptide?

Oxytocin is a peptide hormone known for its role in social bonding, reproduction, and childbirth. It stimulates uterine contractions during childbirth and aids in lactation post-childbirth [1].

Often referred to as the “love hormone,” oxytocin is associated with promoting maternal behaviour and bonding between mother and infant. It also has broader implications for general health and social behavior.

Molecular Formula: C43H66N12O12S2

Sequence: H-Cys(1)-Tyr-Ile-Gln-Asn-Cys(1)-Pro-Leu-Gly-NH2

Molecular Weight: 1007.2 g/mol

View Oxytocin’s HPLC Certificate

Source: PubChem

Oxytocin-Structure
Oxytocin Peptide Vial 2mg

Summary of Oxytocin Benefits:

Buy Oxytocin Peptide Vial for research use here – Available in 2mg peptide vials

Oxytocin Mechanism of Action

Oxytocin, a peptide hormone, is primarily produced in the hypothalamus and subsequently released by the posterior pituitary gland. This hormone plays a crucial role in various physiological and social functions. Upon release, oxytocin travels through the bloodstream and binds to specific oxytocin receptors located on the surface of target cells in different tissues, including the uterus, mammary glands, and brain [2].

In the uterus, oxytocin binds to receptors on smooth muscle cells, activating a signalling cascade that increases intracellular calcium levels. This action leads to enhanced muscle contractions, which are essential during labour to facilitate the birth of a child. In the mammary glands, oxytocin stimulates the contraction of myoepithelial cells surrounding alveoli, promoting milk ejection during breastfeeding [3].

Beyond physical processes, oxytocin influences social and bonding behaviours. In the brain, it acts on neurons involved in emotional and social processing, enhancing feelings of trust, empathy, and bonding. This occurs through the modulation of neurotransmitter systems and the activation of specific neuronal pathways that affect mood and social interactions.

Overall, the mechanism of action of oxytocin involves binding to its receptors, triggering signalling pathways that result in a wide array of physiological and behavioural effects, underscoring its significance in both reproductive and social contexts.

Buy Oxytocin Peptide Nasal Spray for a painless and convenient peptide delivery from PharmaLabGlobal OCEANIA. Choose from 15 ml or 30 ml bottles.

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Potential Clinical Applications of Oxytocin Peptide

The peptide hormone oxytocin is mostly synthesised in the hypothalamus and secreted by the posterior pituitary gland. This hormone is essential for many social and physiological processes. OCEANIA Laboratory research has shown that supplementing with synthetic Oxytocin could have the potential benefits:

Enhances social contact & relationships

OCEANIA Clinical research has found that Oxytocin plays a pivotal role in enhancing social bonding by influencing emotional and social behaviours. Known as the “love hormone,” it fosters feelings of trust, empathy, and connection between individuals [4]. When released, the effect of oxytocin acts on specific brain regions involved in social interactions and emotional processing, modulating neurotransmitter systems to improve mood and social responsiveness. This hormone strengthens relationships by enhancing communication and reducing social anxiety, encouraging individuals to form and maintain strong, cohesive bonds. Through its impact on brain activity, oxytocin not only facilitates intimate connections but also promotes social cohesion within communities, making it essential for healthy social dynamics.

Aids childbirth

Oxytocin aids labour by stimulating uterine contractions, a critical component of the child birth process[2]. Naturally released by the posterior pituitary gland during labour, oxytocin binds to receptors on the uterine muscle cells, leading to a cascade of events that increase intracellular calcium levels. This enhances the frequency and intensity of contractions of the muscles of the uterus, effectively facilitating the progression of labour. In medical settings, synthetic oxytocin, known as Pitocin, is often administered to induce or augment labour when necessary. This helps ensure a smoother labor process by promoting consistent and effective contractions, ultimately aiding in the delivery of the baby.

Can facilitate breast feeding

OCEANIA Studies have demonstrated that Oxytocin plays a vital role in breastfeeding by facilitating the milk ejection reflex. When a baby suckles at the breast, nerve signals trigger the release of oxytocin from the posterior pituitary gland. This hormone then acts on the myoepithelial cells surrounding the alveoli in the mammary glands, causing them to contract. This contraction pushes milk from the alveoli through the milk ducts to the nipple, enabling an efficient flow of milk. By aiding in the effective delivery of milk letdown, oxytocin ensures that breastfeeding is smoother and more productive, benefiting both mother and baby in the bonding and nutritional aspects of feeding [3].

Enhances sexual satisfaction

Oxytocin enhances sexual satisfaction by fostering emotional bonding and intimacy during sexual activity. Often called the “cuddle hormone,” it is released during intimate moments, promoting a deep sense of connection and trust between partners. This hormone helps reduce stress and anxiety, creating a more relaxed and open environment conducive to pleasurable experiences. Oxytocin also plays a role in amplifying the intensity of orgasms through its influence on the neural pathways that mediate pleasure and reward [5]. Studies have found that by facilitating both physiological responses and psychological comfort, oxytocin nasal spray supplementation can significantly contribute to a more satisfying and fulfilling sexual experience [6].

Stress and anxiety reduction

Oxytocin can be beneficial for anxiety by promoting relaxation and reducing stress levels [7]. Oxytocin is known for its calming effects, through it’s ability to mitigate the body’s stress response, making individuals feel more at ease. Oxytocin enhances social interactions, which can alleviate anxiety by fostering connections and trust, reducing feelings of isolation that often accompany anxiety disorders. Studies suggest that oxytocin may influence the brain’s stress-regulating pathways, potentially easing symptoms of anxiety. Its therapeutic applications are being explored, with research indicating that oxytocin administration could offer new avenues for anxiety management, offering a more natural approach to enhancing emotional well-being and resilience against stress.

Cardiovascular benefits

Oxytocin may offer notable cardiovascular benefits by promoting heart health and improving vascular function. It has been shown to help reduce blood pressure, which is crucial for preventing heart-related issues. Oxytocin achieves this by promoting vasodilation, thereby easing blood flow and reducing strain on the heart [8]. Some OCEANIA studies suggest that oxytocin’s ability  to do this can have a calming effect on the cardiovascular system by lowering stress-induced cardiovascular responses.

Additionally, its anti-inflammatory properties may contribute to overall heart health by reducing the risk of atherosclerosis [9]. These findings propose that oxytocin could be a promising agent in enhancing cardiovascular health and well-being.

Buy Oxytocin Pre-Mixed Peptide Pen. Pen kits and pre-mixed refill cartridges supplied by PharmaLabGlobal OCEANIA for research purposes.

Frequently Asked Questions about Oxytocin

Oxytocin Nasal Peptide 30ml

Can Oxytocin help with sexual arousal?

This hormone is naturally released in the body during intimate moments, such as hugging, kissing, and sexual intercourse, which can enhance feelings of closeness and bonding between partners. Scientific studies suggest that Oxytocin can facilitate sexual arousal by promoting sexual receptivity and increasing the emotional connection between partners.

Can Oxytocin cause weight loss?

Some research studies have indicated that Oxytocin can reduce food intake and has an impact on the regulation of body weight. This hormone is thought to interact with the brain’s reward centers, potentially decreasing the desire to consume high-calorie foods, manage cravings and therefore reduce calorie consumption.

In animal studies, Oxytocin has been shown to reduce abdominal fat and improve insulin sensitivity, both of which are beneficial for managing body weight.

However, while these findings are promising, they are not yet conclusive, and more research is needed to fully understand Oxytocin’s role in weight management and its potential application in treating obesity in humans. 

 

Are there any side effects associated with the use of Oxytocin?

Common side effects of Oxytocin administration may include nausea, vomiting, and headaches. Some individuals might experience more specific reactions such as dizziness, increased heart rate, or allergic reactions, though these are less common.

Despite these potential side effects, Oxytocin is considered a valuable therapeutic agent, and prescription medications, for its role in inducing labour, controlling bleeding after childbirth, and potentially providing other health benefits, such as influencing emotional responses and social bonding. You should consult with a healthcare provider before considering Oxytocin. 

Scientific Research

[1] Carter CS, Kenkel WM, MacLean EL, Wilson SR, Perkeybile AM, Yee JR, Ferris CF, Nazarloo HP, Porges SW, Davis JM, Connelly JJ, Kingsbury MA. Is Oxytocin “Nature’s Medicine”? Pharmacol Rev. 2020 Oct;72(4):829-861. 

[2] Walter MH, Abele H, Plappert CF. The Role of Oxytocin and the Effect of Stress During Childbirth: Neurobiological Basics and Implications for Mother and Child. Front Endocrinol (Lausanne). 2021 Oct 27;12:742236. 

[3] Tria Astika Endah Permatasari, Amir Syafruddin, The relationship between oxytocin levels with empathy and breastfeeding intention in female medical students: A cross-sectional study, Annals of Medicine and Surgery, Volume 81, 2022, 104486.

[4] Shan Gao, Benjamin Becker, Lizhu Luo et al. Oxytocin, the peptide that bonds the sexes also divides them, Research Article Neuroscience, Vol. 113 | No. 27.

[5] Melis MR, Argiolas A. Oxytocin, Erectile Function and Sexual Behavior: Last Discoveries and Possible Advances. Int J Mol Sci. 2021 Sep 26;22(19):10376.

[6] MacDonald K, Feifel D. Dramatic improvement in sexual function induced by intranasal oxytocin. J Sex Med. 2012 May;9(5):1407-10.

[7] Takayanagi Y, Onaka T. Roles of Oxytocin in Stress Responses, Allostasis and Resilience. Int J Mol Sci. 2021 Dec 23;23(1):150.

[8] Jankowski M, Broderick TL, Gutkowska J. The Role of Oxytocin in Cardiovascular Protection. Front Psychol. 2020 Aug 25;11:2139. 

[9] Wang P, Wang SC, Yang H, Lv C, Jia S, Liu X, Wang X, Meng D, Qin D, Zhu H, Wang YF. Therapeutic Potential of Oxytocin in Atherosclerotic Cardiovascular Disease: Mechanisms and Signaling Pathways. Front Neurosci. 2019 May 21;13:454. 

Further Reading:

Revolutionising Fertility Treatment with HCG

This blog delves into the diverse roles of HCG, emphasizing its ability to boost success rates in assisted reproductive technologies. It also explores the exciting potential of combining Kisspeptin, Oxytocin, and PT-141, offering insight into their synergistic effects.

Peptides for Anxiety

How Peptides Can Help You Manage Anxiety

This blog explores the use of peptides as a natural alternative for managing anxiety, offering a comprehensive guide on their benefits. It highlights specific peptides like Selank, Oxytocin, and Semax, detailing how they interact with the body to alleviate anxiety symptoms. 

Peptides for Mental Health

This blog highlights peptides like Selank, which regulates serotonin and dopamine to improve mood and cognitive function; Semax, known for boosting brain-derived neurotrophic factor to enhance memory and Oxytocin, which promotes social bonding and reduces stress.

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